Mark Abe

Associate Professor
Biosciences Graduate Program Association
  1. Moore PE, Poston JT, Boyer D, Barsky E, Gaffin J, Boyne KB, Ross KR, Mann Dosier LB, Vece TJ, Casey AM, Welsh SK, Logan JW, Shepherd EG, Phinzy PA, Panitch HB, Papantonakis CM, Austin ED, Orandi AB, Kitcharoensakkul M, Abe MK, Horani A, Rettig JS, Pittman J. ATS Core Curriculum 2017: Part II. Pediatric Pulmonary Medicine. Ann Am Thorac Soc. 2017 08; 14(Suppl_2):S165-S181. View in: PubMed

  2. Doebele RC, Schulze-Hoepfner FT, Hong J, Chlenski A, Zeitlin BD, Goel K, Gomes S, Liu Y, Abe MK, Nor JE, Lingen MW, Rosner MR. A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis. Blood. 2009 Nov 12; 114(20):4592-600. View in: PubMed

  3. White SR, Martin LD, Abe MK, Marroquin BA, Stern R, Fu X. Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2009 Jul; 297(1):L164-73. View in: PubMed

  4. Claud EC, Lu J, Wang XQ, Abe M, Petrof EO, Sun J, Nelson DJ, Marks J, Jilling T. Platelet-activating factor-induced chloride channel activation is associated with intracellular acidosis and apoptosis of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1191-200. View in: PubMed

  5. Liu Y, Martinez L, Ebine K, Abe MK. Role for mitogen-activated protein kinase p38 alpha in lung epithelial branching morphogenesis. Dev Biol. 2008 Feb 01; 314(1):224-35. View in: PubMed

  6. Saelzler MP, Spackman CC, Liu Y, Martinez LC, Harris JP, Abe MK. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5. J Biol Chem. 2006 Jun 16; 281(24):16821-32. View in: PubMed

  7. Zhou L, Goldsmith AM, Bentley JK, Jia Y, Rodriguez ML, Abe MK, Fingar DC, Hershenson MB. 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy. Am J Respir Cell Mol Biol. 2005 Aug; 33(2):195-202. View in: PubMed

  8. Kuo WL, Duke CJ, Abe MK, Kaplan EL, Gomes S, Rosner MR. ERK7 expression and kinase activity is regulated by the ubiquitin-proteosome pathway. J Biol Chem. 2004 May 28; 279(22):23073-81. View in: PubMed

  9. Funkhouser AW, Kang JA, Tan A, Li J, Zhou L, Abe MK, Solway J, Hershenson MB. Rhinovirus 16 3C protease induces interleukin-8 and granulocyte-macrophage colony-stimulating factor expression in human bronchial epithelial cells. Pediatr Res. 2004 Jan; 55(1):13-8. View in: PubMed

  10. Abe MK, Saelzler MP, Espinosa R, Kahle KT, Hershenson MB, Le Beau MM, Rosner MR. ERK8, a new member of the mitogen-activated protein kinase family. J Biol Chem. 2002 May 10; 277(19):16733-43. View in: PubMed

  11. Abe MK, Kahle KT, Saelzler MP, Orth K, Dixon JE, Rosner MR. ERK7 is an autoactivated member of the MAPK family. J Biol Chem. 2001 Jun 15; 276(24):21272-9. View in: PubMed

  12. Hershenson MB, Abe MK. Mitogen-activated signaling in airway smooth muscle. A central role for Ras. Am J Respir Cell Mol Biol. 1999 Dec; 21(6):651-4. View in: PubMed

  13. Abe MK, Kuo WL, Hershenson MB, Rosner MR. Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth. Mol Cell Biol. 1999 Feb; 19(2):1301-12. View in: PubMed

  14. Qian Z, Okuhara D, Abe MK, Rosner MR. Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel. J Biol Chem. 1999 Jan 15; 274(3):1621-7. View in: PubMed

  15. Abe MK, Kartha S, Karpova AY, Li J, Liu PT, Kuo WL, Hershenson MB. Hydrogen peroxide activates extracellular signal-regulated kinase via protein kinase C, Raf-1, and MEK1. Am J Respir Cell Mol Biol. 1998 Apr; 18(4):562-9. View in: PubMed

  16. Chao TS, Abe M, Hershenson MB, Gomes I, Rosner MR. Src tyrosine kinase mediates stimulation of Raf-1 and mitogen-activated protein kinase by the tumor promoter thapsigargin. Cancer Res. 1997 Aug 01; 57(15):3168-73. View in: PubMed

  17. Karpova AY, Abe MK, Li J, Liu PT, Rhee JM, Kuo WL, Hershenson MB. MEK1 is required for PDGF-induced ERK activation and DNA synthesis in tracheal myocytes. Am J Physiol. 1997 Mar; 272(3 Pt 1):L558-65. View in: PubMed

  18. Kuo WL, Abe M, Rhee J, Eves EM, McCarthy SA, Yan M, Templeton DJ, McMahon M, Rosner MR. Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells. Mol Cell Biol. 1996 Apr; 16(4):1458-70. View in: PubMed

  19. Nagae A, Abe M, Becker RP, Deddish PA, Skidgel RA, Erdös EG. High concentration of carboxypeptidase M in lungs: presence of the enzyme in alveolar type I cells. Am J Respir Cell Mol Biol. 1993 Aug; 9(2):221-9. View in: PubMed

  20. Hershenson MB, Kelleher MD, Naureckas ET, Abe MK, Rubinstein VJ, Zimmermann A, Bendele AM, McNulty JA, Panettieri RA, Solway J. Hyperoxia increases airway cell S-phase traversal in immature rats in vivo. Am J Respir Cell Mol Biol. 1994 Sep; 11(3):296-303. View in: PubMed

  21. Hershenson MB, Abe MK, Kelleher MD, Naureckas ET, Garland A, Zimmermann A, Rubinstein VJ, Solway J. Recovery of airway structure and function after hyperoxic exposure in immature rats. Am J Respir Crit Care Med. 1994 Jun; 149(6):1663-9. View in: PubMed

  22. Abe MK, Chao TS, Solway J, Rosner MR, Hershenson MB. Hydrogen peroxide stimulates mitogen-activated protein kinase in bovine tracheal myocytes: implications for human airway disease. Am J Respir Cell Mol Biol. 1994 Nov; 11(5):577-85. View in: PubMed

  23. Naureckas ET, Hershenson MB, Abe MK, Kelleher MD, Florio C, Heisler SI, Absher M, Evans JN, Samsel RW, Solway J. Bronchoalveolar lavage fluid from immature rats with hyperoxia-induced airway remodeling is mitogenic for airway smooth muscle. Am J Respir Cell Mol Biol. 1995 Mar; 12(3):268-74. View in: PubMed

  24. Hershenson MB, Chao TS, Abe MK, Gomes I, Kelleher MD, Solway J, Rosner MR. Histamine antagonizes serotonin and growth factor-induced mitogen-activated protein kinase activation in bovine tracheal smooth muscle cells. J Biol Chem. 1995 Aug 25; 270(34):19908-13. View in: PubMed

  25. Kelleher MD, Abe MK, Chao TS, Jain M, Green JM, Solway J, Rosner MR, Hershenson MB. Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis. Am J Physiol. 1995 Jun; 268(6 Pt 1):L894-901. View in: PubMed

  26. Abe M, Nakamura F, Tan F, Deddish PA, Colley KJ, Becker RP, Skidgel RA, Erdös EG. Expression of rat kallikrein and epithelial polarity in transfected Madin-Darby canine kidney cells. Hypertension. 1995 Dec; 26(6 Pt 1):891-8. View in: PubMed

  27. Nagae A, Deddish PA, Becker RP, Anderson CH, Abe M, Tan F, Skidgel RA, Erdös EG. Carboxypeptidase M in brain and peripheral nerves. J Neurochem. 1992 Dec; 59(6):2201-12. View in: PubMed