Studying how cancer cells adapt to and survive under the nutritional context of the tumor microenvironment (TME). Building a multi-omics based metabolic profile of pancreatic ductal adenocarcinoma (PDAC) cells under TME nutrient levels.
Working at the interface of the research lab and clinic, our group is identifying mechanisms of resistance to anti-androgen therapies in advanced prostate cancer and translating these discoveries into improved treatment strategies for patients.
My previous research at Ohio University investigated ATP as a modulator of epithelial to mesenchymal transition / metastasis in lung cancer. My current research interests are in blood cancers, cancer immunology, cancer metabolism, and metastasis.
My work investigates statistical modeling approaches for drug prediction and drug discovery. By contextualizing patterns of cell line drug response in patients, we aim to predict and evaluate drugs effective in triple-negative breast cancers
Exploring stapled peptides as a tool for interrupting protein-protein interactions in order to manipulate the immune system with the overall goal of improving existing immunotherapies and generating new strategies for the treatment of cancer.