Professor of Pediatrics
Section of Hematology/Oncology and Stem Cell Transplantation
University of Chicago
AB - Biological SciencesUCSD
PHD - Physiology and PharmacologyUCSD
MD - MedicineChildren's Hospital
Boston
Internship and Residency - PediatricsChildren's Hospital and Dana Farber Cancer Center
Boston
Fellowship - Pediatric Hematology/OncologyConnexin channels and hemichannels are modulated differently by charge reversal at residues forming the intracellular pocket.
Connexin channels and hemichannels are modulated differently by charge reversal at residues forming the intracellular pocket. Biol Res. 2024 May 23; 57(1):31.
PMID: 38783330Pediatric cataracts of different etiologies contain insoluble, calcified particles.
Pediatric cataracts of different etiologies contain insoluble, calcified particles. Front Ophthalmol (Lausanne). 2023; 3.
PMID: 37441058A crystallin mutant cataract with mineral deposits.
A crystallin mutant cataract with mineral deposits. J Biol Chem. 2023 08; 299(8):104935.
PMID: 37331601Editorial: Ion channels, pumps, and transporters in lens physiology and disease.
Editorial: Ion channels, pumps, and transporters in lens physiology and disease. Front Physiol. 2022; 13:1071215.
PMID: 36406990Loss of fiber cell communication may contribute to the development of cataracts of many different etiologies.
Loss of fiber cell communication may contribute to the development of cataracts of many different etiologies. Front Physiol. 2022; 13:989524.
PMID: 36171977Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice.
Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice. Cells. 2022 09 07; 11(18).
PMID: 36139360Connexin Mutants Cause Cataracts Through Deposition of Apatite.
Connexin Mutants Cause Cataracts Through Deposition of Apatite. Front Cell Dev Biol. 2022; 10:951231.
PMID: 35938173Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease.
Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease. J Clin Med. 2022 Feb 03; 11(3).
PMID: 35160266Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation.
Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation. J Biol Chem. 2022 03; 298(3):101673.
PMID: 35120923Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant.
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Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant. Biophys J. 2021 12 21; 120(24):5644-5656.
PMID: 34762867American Society for Clinical Investigation
Society for Pediatric Research
Fellow, American Heart Association
Fellow, Association for Research in Vision and Ophthalmology