Stanford University
Stanford, CA
Post-doc - Structural biology, Immunology
2018University of Texas Southwestern Medical Center at Dallas
Dallas, TX
Ph.D. - Molecular biophysics w/ emphasis in computational and systems biology
2011San Francisco State University
San Francisco, CA
B.S. - Biochemistry
2003Structural studies of the IFN?4 receptor complex using cryoEM enabled by protein engineering.
Structural studies of the IFN?4 receptor complex using cryoEM enabled by protein engineering. Nat Commun. 2025 Jan 18; 16(1):818.
PMID: 39827213Structural insights into the formation of repulsive netrin guidance complexes.
Structural insights into the formation of repulsive netrin guidance complexes. Sci Adv. 2024 Feb 16; 10(7):eadj8083.
PMID: 38363837Molecular analysis of the type III interferon complex and its applications in protein engineering.
Molecular analysis of the type III interferon complex and its applications in protein engineering. Biophys J. 2023 11 07; 122(21):4254-4263.
PMID: 37794680Recent and future perspectives on engineering interferons and other cytokines as therapeutics.
Recent and future perspectives on engineering interferons and other cytokines as therapeutics. Trends Biochem Sci. 2023 03; 48(3):259-273.
PMID: 36241490Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker.
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker. Nat Biomed Eng. 2022 07; 6(7):819-829.
PMID: 35534574Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.
Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes. Cell. 2018 01 25; 172(3):549-563.e16.
PMID: 29275860Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers.
Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers. Elife. 2017 05 12; 6.
PMID: 28498099The IFN-?-IFN-?R1-IL-10Rß Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.
The IFN-?-IFN-?R1-IL-10Rß Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity. Immunity. 2017 03 21; 46(3):379-392.
PMID: 28329704Deconstructing the peptide-MHC specificity of T cell recognition.
Deconstructing the peptide-MHC specificity of T cell recognition. Cell. 2014 May 22; 157(5):1073-87.
PMID: 24855945Requirements for efficient correction of ?F508 CFTR revealed by analyses of evolved sequences.
Requirements for efficient correction of ?F508 CFTR revealed by analyses of evolved sequences. Cell. 2012 Jan 20; 148(1-2):164-74.
PMID: 22265409Career Development Award (K01)
NIH, NCI
2013 - 2018Fellowship
Helen Hay Whitney Foundation
2013Fellowship
Damon Runyon Cancer Research Foundation
2012Dean’s Discretionary Award – Academic and Research Excellence
UTSW
2011Best Graduate Student Poster, Molecular Biophysics Annual Symposium
UTSW
2011Fellowship, Louis Stokes Alliance for Minority Participation
NSF
2004 - 2005Edwin Motel Award – Most Promising Student
SFSU
2004Post-Baccalaureate Research Education Program
NIH
2003 - 2004
Juan Mendoza
- Assistant Professor of Pritzker School of Molecular Engineering
- Websites: The Mendoza Lab, Research Network Profile
- Contact: jlmendoza@uchicago.edu
- Graduate Programs: Biochemistry and Molecular Biophysics, Committee on Cancer Biology, Committee on Immunology