Faculty

Akash Patnaik, MD PhD

Spatial statistics infer structured immune signatures in primary prostate cancer.
Spatial statistics infer structured immune signatures in primary prostate cancer. Cancer Immunol Res. 2026 Sep 11.
PMID: 42726512

CD73 inhibition overcomes adaptive immune resistance to PARP inhibition in models of prostate cancer.
CD73 inhibition overcomes adaptive immune resistance to PARP inhibition in models of prostate cancer. J Clin Invest. 2026 Oct 01; 136(19).
PMID: 42611560

B7-H3 Gene Expression Shapes Prognosis and Therapeutic Opportunities across Patient Groups with Prostate Cancer.
B7-H3 Gene Expression Shapes Prognosis and Therapeutic Opportunities across Patient Groups with Prostate Cancer. Clin Cancer Res. 2026 Aug 03; 32(15):3381-3394.
PMID: 42012455

Integrated Single-Cell Profiling Reveals Dichotomous NK Cell Populations Associated with Immunosuppression in Solid Tumors.
Integrated Single-Cell Profiling Reveals Dichotomous NK Cell Populations Associated with Immunosuppression in Solid Tumors. Cancer Immunol Res. 2026 Jun 02; 14(6):1008-1021.
PMID: 41758966

Nivolumab plus ipilimumab for chemotherapy-refractory metastatic castration-resistant prostate cancer: results from the randomized portion of the phase 2 CheckMate 650 trial.
Nivolumab plus ipilimumab for chemotherapy-refractory metastatic castration-resistant prostate cancer: results from the randomized portion of the phase 2 CheckMate 650 trial. Nat Commun. 2026 May 08; 17(1).
PMID: 42098105

Correction: Natural killer cell infiltration in prostate cancers predict improved patient outcomes.
Correction: Natural killer cell infiltration in prostate cancers predict improved patient outcomes. Prostate Cancer Prostatic Dis. 2025 Dec; 28(4):1030.
PMID: 40796671

HLA class I expression shapes the tumor immune microenvironment and influences prognosis in prostate cancer.
HLA class I expression shapes the tumor immune microenvironment and influences prognosis in prostate cancer. Prostate Cancer Prostatic Dis. 2026 Jun; 29(2):425-434.
PMID: 41139148

Spatially organized lymphocytic microenvironments in high grade primary prostate tumors.
Spatially organized lymphocytic microenvironments in high grade primary prostate tumors. bioRxiv. 2025 Sep 21.
PMID: 41000797

Single-Cell and Spatial Transcriptomics Reveal a Tumor-Associated Macrophage Subpopulation that Mediates Prostate Cancer Progression and Metastasis.
Single-Cell and Spatial Transcriptomics Reveal a Tumor-Associated Macrophage Subpopulation that Mediates Prostate Cancer Progression and Metastasis. Mol Cancer Res. 2025 07 02; 23(7):653-665.
PMID: 40105746

Natural Killer Cell Infiltration in Prostate Cancers Predict Improved Patient Outcomes.
Natural Killer Cell Infiltration in Prostate Cancers Predict Improved Patient Outcomes. Prostate Cancer Prostatic Dis. 2025 Mar; 28(1):129-137.
PMID: 38418892

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