Our laboratory is interested in the molecular signals that are used by the immune system to distinguish healthy from unhealthy tissue. Many of our projects focus on “unconventional” T cell recognition, involving γδ T cells, Natural Killer T cells and Muscosal-Associated Invariant T (MAIT) cells and antigen presentation by nonclassical or MHC-like proteins. Our strengths are in biochemistry, structural biology, protein engineering and cellular assays that will reveal the fundamental principles behind how effector cells of the immune system regulate human disease. We have a high level of expertise in studying molecular recognition of T cells, particularly unconventional T cells outside the canonical CD4+/CD8+ lineage and structure function of antigen-presenting molecules.
Erin June Adams, PhD
- Joseph Regenstein Professor of Biochemistry and Molecular Biology
- Research and Scholarly Interests: biochemistry, MHC (nonclassical and MHC-like), Molecular Immunology, structural biology, T Cells
- Websites: Lab website, Research Network Profile
- Contact: ejadams@uchicago.edu
- Graduate Programs: Biochemistry & Molecular Biophysics, Biochemistry and Molecular Biophysics, Committee on Cancer Biology, Committee on Genetics, Genomics and Systems Biology, Committee on Immunology, UChicago Biosciences