Amittha Wickrema, PhD

Enrichment of CD4+ and CD8+ T lymphocytes with a column-free flow-based device for clinical cell manufacturing.
Enrichment of CD4+ and CD8+ T lymphocytes with a column-free flow-based device for clinical cell manufacturing. Cytotherapy. 2025 Jan 02.
PMID: 39891633

PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation.
PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation. Blood Cancer Discov. 2022 09 06; 3(5):444-467.
PMID: 35820129

Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations.
Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations. Elife. 2022 08 30; 11.
PMID: 36040792

BET inhibitors enhance embryonic and fetal globin expression in erythroleukemia cell lines.
BET inhibitors enhance embryonic and fetal globin expression in erythroleukemia cell lines. Haematologica. 2021 12 01; 106(12):3223-3227.
PMID: 34435481

The demise of islet allotransplantation in the United States: A call for an urgent regulatory update.
The demise of islet allotransplantation in the United States: A call for an urgent regulatory update. Am J Transplant. 2021 04; 21(4):1365-1375.
PMID: 33251712

Epigenetic modifiers in normal and aberrent erythropoeisis.
Epigenetic modifiers in normal and aberrent erythropoeisis. Semin Hematol. 2021 01; 58(1):15-26.
PMID: 33509439

Navigating Dilemmas in Treatment Choice: Our Approach to Supplemental Apheresis Prior to Enrollment in Early- Phase Cellular Therapy Clinical Trials.
Navigating Dilemmas in Treatment Choice: Our Approach to Supplemental Apheresis Prior to Enrollment in Early- Phase Cellular Therapy Clinical Trials. Transplant Cell Ther. 2021 02; 27(2):105-107.
PMID: 33781544

The Demise of Islet Allotransplantation in the US: A Call for an Urgent Regulatory Update The "ISLETS FOR US" Collaborative.
Witkowski P, Philipson L, Kaufman DB, Ratner L, Abouljoud MS, Bellin M, Buse J, Kandeel F, Stock P, Mulligan D, Markmann JF, Kozlowski T, Andreoni K, Alejandro R, Baidal D, Hardy MA, Wickrema A, Mirmira RG, Fung J, Becker Y, Josephson MA, Bachul PJ, Pyda JS, Charlton M, Millis JM, Gaglia J, Stratta RJ, Fridell JA, Niederhaus S, Forbes RC, Jayant K, Robertson RP, Odorico J, Levy M, Harland R, Abrams PL, Olaitan OK, Kandaswamy R, Wellen J, Japour AJ, Desai CS, Naziruddin B, Balamurugan AN, Barth RN, Ricordi C. The Demise of Islet Allotransplantation in the US: A Call for an Urgent Regulatory Update The "ISLETS FOR US" Collaborative. Am J Transplant. 2020 Nov 29.
PMID: 33251712

HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia.
HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia. Blood Adv. 2020 07 14; 4(13):3053-3062.
PMID: 32634239

Heterogeneity of Red Blood Cells: Causes and Consequences.
Heterogeneity of Red Blood Cells: Causes and Consequences. Front Physiol. 2020; 11:392.
PMID: 32457644