Faculty

Alexander T Pearson, MD PhD

The Pearson Lab integrates clinical expertise, mathematical modeling, high dimensional statistics, and basic tumor biology methods to investigate and propose new treatments for head and neck cancer.

University of Michigan
Ann Arbor, MI
Fellowship - Hematology/Oncology
2016

University of Michigan
Ann Arbor, MI
Postdoctoral Fellowship - Nor Lab (2013-2017)
2016

University of Michigan
Ann Arbor, MI
Residency - Internal Medicine
2012

University of Rochester
Rochester, NY
MD - Medicine
2010

University of Rochester
Rochester, NY
PhD - Statistics
2009

Cornell University
Ithaca, NY
BS - Biometry and Statistics
2002

Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC.
Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC. Nat Med. 2026 Sep; 32(9):3235-3247.
PMID: 42733093

Counterfactual Diffusion Models Provide Interpretable Explanations of Artificial Intelligence Models in Pathology.
Counterfactual Diffusion Models Provide Interpretable Explanations of Artificial Intelligence Models in Pathology. Cancer Res. 2026 09 02; 86(17):4414-4433.
PMID: 42308255

Applications of Deep Learning in Endocrine Neoplasms.
Applications of Deep Learning in Endocrine Neoplasms. Clin Lab Med. 2026 Sep; 46(3):629-641.
PMID: 42526978

Comprehensive multi-omic dissection and AI-prioritized target identification in inverted papilloma-associated sinonasal squamous cell carcinoma.
Comprehensive multi-omic dissection and AI-prioritized target identification in inverted papilloma-associated sinonasal squamous cell carcinoma. NPJ Precis Oncol. 2026 Jul 10.
PMID: 42432132

Living evidence-informed guideline on the early detection of oral squamous cell carcinoma and potentially malignant disorders: Light-based adjuncts to determine the need for biopsy, Version 2026 1.0.
Living evidence-informed guideline on the early detection of oral squamous cell carcinoma and potentially malignant disorders: Light-based adjuncts to determine the need for biopsy, Version 2026 1.0. J Am Dent Assoc. 2026 Sep; 157(9):968-979.
PMID: 42227938

Accessible Clinical Tool for Prognosis and Chemotherapy Prediction in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer in Diverse and Low-Resource Settings.
Accessible Clinical Tool for Prognosis and Chemotherapy Prediction in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer in Diverse and Low-Resource Settings. JCO Glob Oncol. 2026 May; 12(5):e2500705.
PMID: 42214047

Development and Validation of a Multimodal Clinical, Pathologic, and Genomic Model for Breast Cancer Recurrence.
Development and Validation of a Multimodal Clinical, Pathologic, and Genomic Model for Breast Cancer Recurrence. medRxiv. 2026 May 12.
PMID: 42180367

Prediction of OncotypeDX recurrence score using hematoxylin and eosin-stained whole slide images.
Prediction of OncotypeDX recurrence score using hematoxylin and eosin-stained whole slide images. NPJ Breast Cancer. 2026 May 11; 12(1).
PMID: 42115215

Artificial intelligence model predicts malignant transformation of oral leukoplakia and optimizes interventions.
Artificial intelligence model predicts malignant transformation of oral leukoplakia and optimizes interventions. Oral Oncol. 2026 Jul; 178:107982.
PMID: 42107221

Histology-Derived Signatures Predict Recurrence Risk and Chemotherapy Benefit in Randomized Trials of Early Breast Cancer.
Histology-Derived Signatures Predict Recurrence Risk and Chemotherapy Benefit in Randomized Trials of Early Breast Cancer. medRxiv. 2026 May 05.
PMID: 42078387

View All Publications

Mark Roth Award
University of Michigan
2015

Chief Fellow in Hematology/Oncology
University of Michigan
2014 - 2015