Bakhtiar Yamini

Education
  • University of Chicago Medicine, Residency Neurological Surgery
  • University of Chicago Medicine, Internship General Surgery
  • University of Michigan Medical School, MD
Biosciences Graduate Program Association
Publications
  1. Gholampour S, Patel J, Yamini B, Frim D. Cerebrospinal fluid hydrocephalus shunting: cisterna magna, ventricular frontal, ventricular occipital. Neurosurg Rev. 2022 May 05. View in: PubMed

  2. Bernal GM, Wu L, Voce DJ, Weichselbaum RR, Yamini B. p52 signaling promotes cellular senescence. Cell Biosci. 2022 Apr 04; 12(1):43. View in: PubMed

  3. Kim M, Ladomersky E, Mozny A, Kocherginsky M, O'Shea K, Reinstein ZZ, Zhai L, Bell A, Lauing KL, Bollu L, Rabin E, Dixit K, Kumthekar P, Platanias LC, Hou L, Zheng Y, Wu J, Zhang B, Hrachova M, Merrill SA, Mrugala MM, Prabhu VC, Horbinski C, James CD, Yamini B, Ostrom QT, Johnson MO, Reardon DA, Lukas RV, Wainwright DA. Glioblastoma as an age-related neurological disorder in adults. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab125. View in: PubMed

  4. Du M, Papazian E, Adams D, Caballero N, Portugal L, Das P, Horowitz P, Yamini B, Pinto JM, Roxbury CR. Patient satisfaction with telemedicine is noninferior to in-office visits: Lessons from a tertiary rhinology and endoscopic skull base surgery practice. Int Forum Allergy Rhinol. 2022 05; 12(5):802-804. View in: PubMed

  5. Mansour A, Loggini A, El Ammar F, Alvarado-Dyer R, Polster S, Stadnik A, Das P, Warnke PC, Yamini B, Lazaridis C, Kramer C, Mould WA, Hildreth M, Sharrock M, Hanley DF, Goldenberg FD, Awad IA. Post-Trial Enhanced Deployment and Technical Performance with the MISTIE Procedure per Lessons Learned. J Stroke Cerebrovasc Dis. 2021 Sep; 30(9):105996. View in: PubMed

  6. Lyne SB, Yamini B. An Alternative Pipeline for Glioblastoma Therapeutics: A Systematic Review of Drug Repurposing in Glioblastoma. Cancers (Basel). 2021 Apr 18; 13(8). View in: PubMed

  7. Voce DJ, Bernal GM, Cahill KE, Wu L, Mansour N, Crawley CD, Campbell PS, Arina A, Weichselbaum RR, Yamini B. CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma. Sci Rep. 2021 03 11; 11(1):5665. View in: PubMed

  8. Wu L, Crawley CD, Garofalo A, Nichols JW, Campbell PA, Khramtsova GF, Olopade OI, Weichselbaum RR, Yamini B. p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007. View in: PubMed

  9. Szymura SJ, Bernal GM, Wu L, Zhang Z, Crawley CD, Voce DJ, Campbell PA, Ranoa DE, Weichselbaum RR, Yamini B. DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy. BMC Biol. 2020 03 24; 18(1):32. View in: PubMed

  10. Chiocca EA, Yu JS, Lukas RV, Solomon IH, Ligon KL, Nakashima H, Triggs DA, Reardon DA, Wen P, Stopa BM, Naik A, Rudnick J, Hu JL, Kumthekar P, Yamini B, Buck JY, Demars N, Barrett JA, Gelb AB, Zhou J, Lebel F, Cooper LJN. Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial. Sci Transl Med. 2019 08 14; 11(505). View in: PubMed

  11. Voce DJ, Bernal GM, Wu L, Crawley CD, Zhang W, Mansour NM, Cahill KE, Szymura SJ, Uppal A, Raleigh DR, Spretz R, Nunez L, Larsen G, Khodarev NN, Weichselbaum RR, Yamini B. Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma. Cancer Res. 2019 05 15; 79(10):2536-2548. View in: PubMed

  12. Lyne SB, Polster SP, Fidai S, Pytel P, Yamini B. Primary Sellar Paraganglioma: Case Report with Literature Review and Immunohistochemistry Resource. World Neurosurg. 2019 05; 125:32-36. View in: PubMed

  13. Yamini B. NF-?B, Mesenchymal Differentiation and Glioblastoma. Cells. 2018 Aug 31; 7(9). View in: PubMed

  14. Wu L, Bernal GM, Cahill KE, Pytel P, Fitzpatrick CA, Mashek H, Weichselbaum RR, Yamini B. BCL3 expression promotes resistance to alkylating chemotherapy in gliomas. Sci Transl Med. 2018 07 04; 10(448). View in: PubMed

  15. Young JS, Bernal G, Polster SP, Nunez L, Larsen GF, Mansour N, Podell M, Yamini B. Convection-Enhanced Delivery of Polymeric Nanoparticles Encapsulating Chemotherapy in Canines with Spontaneous Supratentorial Tumors. World Neurosurg. 2018 Sep; 117:e698-e704. View in: PubMed

  16. Hobbs JG, Van Slambrouck C, Miller JL, Yamini B. Intracranial hemorrhage as initial manifestation of plasma cell myeloma: A case report. J Clin Neurosci. 2018 Apr; 50:133-135. View in: PubMed

  17. Young JS, Chmura SJ, Wainwright DA, Yamini B, Peters KB, Lukas RV. Management of glioblastoma in elderly patients. J Neurol Sci. 2017 Sep 15; 380:250-255. View in: PubMed

  18. Schmitt AM, Yamini B. Nfkb1 suppresses DNA alkylation-induced tumor formation. Mol Cell Oncol. 2015 Jan-Mar; 2(1):e968073. View in: PubMed

  19. Cahill KE, Morshed RA, Yamini B. Nuclear factor-?B in glioblastoma: insights into regulators and targeted therapy. Neuro Oncol. 2016 Mar; 18(3):329-39. View in: PubMed

  20. Mansour NM, Bernal GM, Wu L, Crawley CD, Cahill KE, Voce DJ, Balyasnikova IV, Zhang W, Spretz R, Nunez L, Larsen GF, Weichselbaum RR, Yamini B. Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide. Cancer Res. 2015 May 15; 75(10):2039-48. View in: PubMed

  21. Yamini B. Nfkb1/p50 and mammalian aging. Oncotarget. 2015 Feb 28; 6(6):3471-2. View in: PubMed

  22. Crawley CD, Kang S, Bernal GM, Wahlstrom JS, Voce DJ, Cahill KE, Garofalo A, Raleigh DR, Weichselbaum RR, Yamini B. S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability. Cell Cycle. 2015; 14(4):566-76. View in: PubMed

  23. Bernal GM, Wahlstrom JS, Crawley CD, Cahill KE, Pytel P, Liang H, Kang S, Weichselbaum RR, Yamini B. Loss of Nfkb1 leads to early onset aging. Aging (Albany NY). 2014 Nov; 6(11):931-43. View in: PubMed

  24. Voce DJ, Schmitt AM, Uppal A, McNerney ME, Bernal GM, Cahill KE, Wahlstrom JS, Nassiri A, Yu X, Crawley CD, White KP, Onel K, Weichselbaum RR, Yamini B. Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor. Oncogene. 2015 May 21; 34(21):2807-13. View in: PubMed

  25. Bernal GM, LaRiviere MJ, Mansour N, Pytel P, Cahill KE, Voce DJ, Kang S, Spretz R, Welp U, Noriega SE, Nunez L, Larsen GF, Weichselbaum RR, Yamini B. Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma. Nanomedicine. 2014 Jan; 10(1):149-57. View in: PubMed

  26. Crawley CD, Raleigh DR, Kang S, Voce DJ, Schmitt AM, Weichselbaum RR, Yamini B. DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site. Nucleic Acids Res. 2013 Jan; 41(2):764-74. View in: PubMed

  27. Dey M, Daniel S, Wong RH, Smith SM, Yamini B. Marginal zone lymphoma of the thoracic dura causing spinal cord compression. J Clin Neurosci. 2013 Jan; 20(1):171-3. View in: PubMed

  28. Schmitt AM, Crawley CD, Kang S, Raleigh DR, Yu X, Wahlstrom JS, Voce DJ, Darga TE, Weichselbaum RR, Yamini B. p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage. Mol Cell. 2011 Dec 09; 44(5):785-96. View in: PubMed

  29. Rosen DS, Smith S, Gurbuxani S, Yamini B. Extranodal hairy cell leukemia presenting in the lumbar spine. J Neurosurg Spine. 2008 Oct; 9(4):374-6. View in: PubMed

  30. Rosen DS, Shafizadeh S, Baroody FM, Yamini B. Epidural abscess treated with a medial supraorbital craniotomy through an incision in the eyebrow. Case report. J Neurosurg Pediatr. 2008 Feb; 1(2):145-7. View in: PubMed

  31. Ferguson SD, Foster K, Yamini B. Convection-enhanced delivery for treatment of brain tumors. Expert Rev Anticancer Ther. 2007 Dec; 7(12 Suppl):S79-85. View in: PubMed

  32. Yamini B, Yu X, Pytel P, Galanopoulos N, Rawlani V, Veerapong J, Bickenbach K, Weichselbaum RR. Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy. Clin Cancer Res. 2007 Oct 15; 13(20):6217-23. View in: PubMed

  33. Yamini B, Yu X, Dolan ME, Wu MH, Darga TE, Kufe DW, Weichselbaum RR. Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding. Cancer Res. 2007 Jul 15; 67(14):6889-98. View in: PubMed

  34. Sikorski CW, Iteld L, McKinnon M, Yamini B, Frim DM. Correction of sagittal craniosynostosis using a novel parietal bone fixation technique: results over a 10-year period. Pediatr Neurosurg. 2007; 43(1):19-24. View in: PubMed

  35. Sikorski CW, Pytel P, Rubin CM, Yamini B. Intradural spinal Wilm's tumor metastasis: case report. Neurosurgery. 2006 Oct; 59(4):E942-3; discussion E943. View in: PubMed

  36. Yamini B, Narayanan M. Craniopharyngiomas: an update. Expert Rev Anticancer Ther. 2006 Sep; 6 Suppl 9:S85-92. View in: PubMed

  37. Yamini B, Sikorski CW. Surgery for low-grade gliomas: current evidence and controversies. Expert Rev Neurother. 2005 Nov; 5(6 Suppl):S13-9. View in: PubMed

  38. Mezhir JJ, Schmidt H, Yamini B, Senzer NN, Posner MC, Kufe DW, Weichselbaum RR. Chemo-inducible gene therapy. Anticancer Drugs. 2005 Nov; 16(10):1053-8. View in: PubMed

  39. Mezhir JJ, Smith KD, Posner MC, Senzer N, Yamini B, Kufe DW, Weichselbaum RR. Ionizing radiation: a genetic switch for cancer therapy. Cancer Gene Ther. 2006 Jan 01; 13(1):1-6. View in: PubMed

  40. Lee MC, Yamini B, Frim DM. Pseudotumor cerebri patients with shunts from the cisterna magna: clinical course and telemetric intracranial pressure data. Neurosurgery. 2004 Nov; 55(5):1094-9. View in: PubMed

  41. Yamini B, Yu X, Gillespie GY, Kufe DW, Weichselbaum RR. Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. Cancer Res. 2004 Sep 15; 64(18):6381-4. View in: PubMed

  42. Sikorski CW, Yamini B, Frim DM. Endoscopic cyst fenestration outcomes in children one year of age or less. Pediatr Neurosurg. 2004 Mar-Apr; 40(2):59-63. View in: PubMed

  43. Yamini B, Refai D, Rubin CM, Frim DM. Initial endoscopic management of pineal region tumors and associated hydrocephalus: clinical series and literature review. J Neurosurg. 2004 May; 100(5 Suppl Pediatrics):437-41. View in: PubMed

  44. Le H, Yamini B, Frim DM. Lumboperitoneal shunting as a treatment for slit ventricle syndrome. Pediatr Neurosurg. 2002 Apr; 36(4):178-82. View in: PubMed

  45. Zhang ZD, Yamini B, Komuro T, Ono S, Johns L, Marton LS, Weir B, Macdonald RL. Delayed clot removal and experimental vasospasm. Acta Neurochir Suppl. 2001; 77:33-5. View in: PubMed

  46. Macdonald RL, Ono S, Johns L, Marton LS, Weir B, Zhang ZD, Yamini B, Komuro T, Ahmed I, Stoodley M. Molecular weight interactions in experimental vasospasm. Acta Neurochir Suppl. 2001; 77:115-7. View in: PubMed

  47. Zhang ZD, Yamini B, Komuro T, Ono S, Johns L, Marton LS, Weir B, Macdonald RL. Vasospasm in monkeys resolves because of loss of and encasement of subarachnoid blood clot. Stroke. 2001 Aug; 32(8):1868-74. View in: PubMed

  48. Yamini B, Loch Macdonald R, Rosenblum J. Treatment of deep cerebral venous thrombosis by local infusion of tissue plasminogen activator. Surg Neurol. 2001 Jun; 55(6):340-6. View in: PubMed

  49. Ono S, Zhang ZD, Marton LS, Yamini B, Windmeyer E, Johns L, Kowalczuk A, Lin G, Macdonald RL. Heme oxygenase-1 and ferritin are increased in cerebral arteries after subarachnoid hemorrhage in monkeys. J Cereb Blood Flow Metab. 2000 Jul; 20(7):1066-76. View in: PubMed

  50. Yamini B, Goumnerova LC, Frim DM. Endoscopic approach to noncommunicating fluid spaces in the shunted patient. Pediatr Neurosurg. 1999 Nov; 31(5):237-41. View in: PubMed